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Effects of Exercise Intensity and Inorganic Nitrate Supplementation on Vascular Health and Fitness in Post-Menopausal Females Taking Hormone Therapy
The Department of Kinesiology seeks healthy post-menopausal women ages 45-75 taking hormone replacement therapy (MHT) for a research study. The purpose of the study is to improve our understanding of the level of exercise intensity needed for post-menopausal females taking MHT and how taking a beetroot juice supplement to increase blood flow could potentially enhance the benefits of exercise for this group. You may be eligible for this study if: - You are a post-menopausal female. - You are currently taking transdermal hormone therapy (for at least 3 months). - You do not exercise 3x a week or do not exercise regularly. - You do not have cardiovascular disease or diabetes. Study involves exercising 3 times on a bike with total 4 visits to the UVA’s campus. You will be asked to take a nitrate supplement (beetroot juice) or a matching placebo for 3 times- (3 days each with 7 days break). The visits overall will consist of a physical exam, mouth swab, blood and saliva samples, a series of questionnaires, and physical assessment tests. All tests are non-invasive except the blood draws. The researchers will work best with your schedule. Study-related tests, treatment, and exercise training will be provided at no cost. If you are interested or have follow-up questions, please contact Money Ghimire ([email protected]) or Call/text at (434)-924-3004.