Clinical Trials | Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Adolescents and Young Adults with Functional Hypothalamic Amenorrhea
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Adolescents and Young Adults with Functional Hypothalamic Amenorrhea
The Department of Pediatrics seeks young women, ages 14-25 years, who have stopped having menstrual periods to evaluate the effect of two study drugs on bone health. We are looking for young women who have had less than 3 menses in the preceding 6 months. This 12-month-long study involves 9 study visits at the University of Virginia's main campus, and participants will undergo blood draws, bone density scans, and complete questionnaires. We will assess for a bone age at least 14 years old and a BMD Z-score < -1.0 at = 1 skeletal site in order to proceed with study. Participants will be compensated up to $925 for completing all study visits, and there is no cost to them as all study-related investigations are covered. The data we collect may be used to improve care and resources for future patients. For more information, please contact the study team at [email protected], or 434-982-0871.